Can CBD Help Balance Hormones?

14 Minute Read

We’ve all been there. The overwhelm, can’t sleep, hormonal acne, and your emotions are on a never-ending rollercoaster ride. You begin to wonder what is going on and then it dawns you, hormones. Having fluctuating hormones happens to both men and women, but in different ways. This is because we have different endocrine organs and cycles. Nearly every person with female reproductive organs experiences hormone imbalance at some point in their life let alone on a monthly basis. This happens during puberty, menstruation, and pregnancy, and menopause but can occur at any time. A few women may even experience continual, irregular imbalances.

How CBD helps balance hormones. Picture of taking CBD to balance hormones

Hormonal imbalance occurs when your hormones are not at their optimal levels. As a result, even the smallest imbalance can cause an array of unwanted and unexpected effects. The symptoms of hormone imbalance can vary depending on the glands and hormones that have been affected. Here are some symptoms that may indicate an imbalance:

  • Heavy or Irregular periods
  • Excessive sweating
  • Weight loss or gain
  • Mood swings
  • Depression
  • Blurred vision 
  • Insomnia
  • Fatigue
  • Headaches
  • Hair loss or hair change
  • Vaginal dryness
  • Vaginal atrophy
  • Pain during sex
  • Dry skin
  • Acne on the face, chest, or upper back
  • Changes in blood pressure or heart rate

Can CBD Help With Hormonal Balance?

Short answer, yes!  CBD can help with the balancing of hormones. This wonderfully beneficial cannabinoid can be used to influence hormones like cortisol (the stress hormone), melatonin (the sleep hormone) and lastly but not limited to estogren (your sex hormone). Because of this, CBD makes for a great, natural treatment of hormonal imbalances.

To understand how CBD can positively interact with the endocrine system to help balance hormones, let’s take a look at how it works.

Hormones and CBD

Our  bodies are made up of an interconnected network of receptors called theendocannabinoid system (ECS). This system works synergistically with our immune, nervous and endocrine systems and helps regulate key functions in our body such as: stress, mood, sleep, inflammation, pain, metabolism, digestive health, memory, reproduction and last but not least hormones. 

Two important kinds of cannabinoid receptors in the ECS are the CB1 and CB2 receptors. These receptors are found on major glands located throughout the body, and are activated by endocannabinoids. CB1 receptors are located in the central nervous system, primarily in the brain and spinal cord, as well as some organs and tissues.

This includes endocrine glands, and parts of the reproductive, gastrointestinal, and urinary tracts. CB2 receptors involve the peripheral nervous system and play an important role in fighting inflammation. They are mostly found in white blood cells, the tonsils, and in the spleen. When phytocannabinoids such as CBD are introduced into our body they supercharge our ECS creating an optimal balance, or homeostasis in all aspects of functional wellness.

How CBD helps balance hormones. Picture of healthy CBD.

CBD, ECS, and the endocrine connection

CBD indirectly interacts with cannabinoid receptors in the ECS. Because the ECS and endocrine system are closely related, it can also alter the synthesis and secretion of hormones. It does this by working as an antagonist of both CB1 and CB2 receptors. This commonly occurs in the hypothalamus where the CB1 receptor is activated.

The interaction creates altered hormones that are sent to other glands, and upon receiving these messages, send out their own hormones as a response. Since CB1 receptors are found on most other glands and organs, this makes it easy to balance the hormones directly within its network.

CBD also has the ability to increase or decrease the volume and strength of a hormonal message. This is because cannabinoids can weaken or lessen receptors’ sensitivity to a certain hormone.

In order to maintain a balance of our hormones, these messengers must be broken down and disposed of once they have completed their task. This is another thing CBD can help with,  It can maintain the speed of the enzymes that break the hormones down. This is key for a healthy menstrual cycle from brain fog, to mood and digestion.

Now that we have an idea of how CBD can balance hormones, let’s take a look at how it can affect specific ones. Some of the major hormones in our bodies are:

  • Estrogen
  • Thyroid hormones
  • Testosterone
  • Growth hormone
  • Cortisol
  • Insulin

    How CBD helps balance hormones

    CBD and Estrogen

    CBD may lower estrogen levels, but more research is necessary. 

    What we know: CBD may affect estrogen is through increasing the activity of cytochrome p450, enzymes that commonly break estrogen down. This could be key after ovulation as progesterone surges to assist fertilization.

    Estrogen hormones directly affect fertility, sexual development, and possibility of contracting female-related illness like breast cancer.

    The hormones LH and FSH promote ovulation and thus the secretion of estrogen from the ovaries. It has been found that CBD may suppress estrogen production through the inhibition of an enzyme called aromatase, which is commonly used to reduce estrogen in women with breast cancer or post-menopausal.

    CBD and Thyroid Hormones

    Currently there is no research on the impact of CBD and thyroid hormones, but there is information on how endocannabinoids affects them. Thyroid hormones TSH, T3, and T4 all have important functions within the thyroid. Thyroid stimulating hormone (TSH) regulates the production of hormones, while T3 and T4 are connected to weight, energy, hair, skin, nails, and more.

    These hormones are active in the use of our metabolism to carry out these functions. Endocannabinoids, however, reduce thyroid hormones, which in turn reduces the energy needed to carry out the necessary functions.

    And since CBD can either stimulate or diminish the endocannabinoids, this could have an affect on the thyroid. When endocannabinoids are blocked, this increases TSH, T3, and T4, which could contribute to a more active thyroid.

    The effects of CBD may depend on whether the person has an overactive, underactive, or normal thyroid. CBD is known to increase anandamide levels, a fatty acid neurotransmitter. And it has been found that anandamide can diminish TSH in hypothyroidism and normal thyroids, which have high TSH.

    It wouldn’t diminish TSH in those with hyperthyroidism however, which have low TSH. This could possibly mean that CBD could adapt based on a person’s needs. More evidence is needed, but the future looks bright for CBD’s treatment of thyroid hormones.

    CBD and Testosterone

    Along with estrogen, testosterone helps with the growth, maintenance, and repair of women’s bone mass and reproductive tissues. It can also affect behavior. Having an imbalance of testosterone may lead to a decrease in sex drive, particularly in pre- and post-menopausal women.

    Testosterone comes from the male and female reproductive organs in response to the hormones LH and FSH from the hypothalamus. High doses of CBD may affect LH and FSH levels, but more evidence is needed to prove it will have an effect on testosterone in turn. Some researchers speculate that CBD may even have a negative effect on testosterone if used at high doses for a long time without exercise.

    But CBD may help stimulate testosterone production in other ways. Physical and mental stress can lead to lower testosterone levels. CBD may limit the production of stress hormones prolactin and cortisol which slow the production of testosterone.

    CBD and Cortisol

    The infamous stress hormone cortisol notifies the body when something stressful is occurring. Cortisol comes from the adrenals in response to sensory inputs from the hypothalamus. Though this hormone may be beneficial in small spikes that occur during an emergency it's not one we wanted hanging around on the daily.

    Anxiety can help us perceive many things as potential danger, such as the possibility of losing our jobs, fights threatening our relationships, or bills piling up. These stimuli can cause chronic cortisol output due to stress that has been unresolved. Known for its anti-anxiety benefits, CBD is the ultimate antidote to stress. CBD has the ability to interrupt the stress response through CB1 receptors in the hypothalamus and Cortisol production is halted as a result.

    CBD and Growth Hormone

    The growth hormone (GH) is responsible for growth and development in our bodies. This is done through the signaling of cell reproduction and regeneration. Increased growth hormone could lead to stronger bones, more muscle mass, and more energy.

    Long term use of CBD may affect GH. It has been shown that a single dose will have no effect on GH levels. However, other cannabinoids such as THC have been shown to reduce GH through its interaction of the CB1 receptor. Since CBD also has an affinity for the CB1 receptor, this could mean it may affect GH as well. Whether or not CBD causes a positive effect still remains to be seen since more research is needed.

    CBD and Insulin

    Insulin is a hormone which deals with energy and how much is used and stored. It helps with the regulation of our metabolism, which has an effect on weight and energy levels.

    A normal insulin level uses sugar efficiently in our muscles and liver, and not much is left to be stored in fat. High insulin levels cause weight gain and diabetes. This is often brought on by high sugar consumption.

    Some research shows that CBD can reduce high insulin levels and keep blood sugar low. It may stimulate cells in the muscles and liver to efficiently absorb sugar, thus stabilizing blood sugar. Though it’s not proved, it may be  possible that through reducing insulin levels, CBD may help reduce weight.

    How CBD helps balance hormones. Picture of CBD bottle on towel.

    Try Third Party Tested, Full-Spectrum CBD for Hormone Balance

    Consult your doctor if you are interested in using CBD for your hormonal imbalance. If you decide to give it a try, be sure to purchase a product that has been third party tested. Even though Hemp and CBD are FDA approved the industry is currently under regulated like most supplements. This means there are a lot of untested products out there that make false claims or may even contain harmful contaminants.

    To balance your hormones, we recommend a full-spectrum product, meaning it that contains a range of cannabinoids found naturally in hemp. This combination allows for the compounds to work synergistically, mimicking nature. This amplifies the product’s overall effects. Although CBD comes in varying forms such as oil drops, capsules, edibles, and drinks, we find that CBD oil is the most effective convenient choice.

    Make sure to take the recommended dose for your condition, and do so consistently. The best results occur when CBD has compounded over time. Use it daily!

    What are Hormones and the Endocrine System?

    To understand unbalanced hormones and how to balance them again, it is first important to understand how the endocrine system works. Many of us tend to only pay attention to hormones during PMS, pregnancy and menopause, and often overlook the varying functions they play every single day.  So let’s take a closer look at this very important system that has a huge impact on our day-to-day lives.

    The endocrine system in the human body is made up of glands that produce hormones. This system regulate things like:

    • - Metabolism
    • - Tissue function 
    • - Sexual function 
    • - Growth and development 
    • - Reproduction
    • - Sleep
    • - Blood pressure
    • - Body temperature 
    • - Appetite
    • - Mood


    Hormones are small, powerful chemical messengers within the endocrine system that control these functions. The hormonal messages are sent and received through endocrine glands to receptors in our organs and tissues. These glands are located throughout our bodies, forming a communication network to maintain efficient bodily functions. The major endocrine glands are:

    • In the brain: the hypothalamus, pituitary gland, and pineal gland
    • Above the kidneys: the adrenal glands
    • In the groin: the ovaries or testicles
    • The neck: the thyroid and parathyroids
    • In the abdomen: the pancreas


    Hormones are essential for all body processes and thus having too many or too little can affect your health. Hormonal imbalance occurs when the glands produce too little, or too many hormones. There may even be a full stop of hormone production altogether.

    Your hormone levels can fluctuate depending on the time of day as well as what life stage you are in. They can become imbalanced during any life stage. These imbalances can cause or be caused by illnesses or triggered by our environment. For instance, an environment that is toxic with plastics, industrial chemicals, and pesticides can wreak major havoc on our hormones.

    How CBD helps balance hormones. A woman under stress with her hand on her face.

    Here are a list of possible triggers that cause imbalances:

    • - Tumors of the endocrine glands
    • - Diabetes
    • - Polycystic ovary syndrome 
    • - Cushing’s syndrome
    • - Addison’s disease
    • - Underactive thyroid (hypothyroidism)
    • - Overactive thyroid (hyperthyroidism)
    • - Chronic stress
    • - Birth control or hormone replacement
    • - Poor diet
    • - Being overweight
    • - Exposure to endocrine disruptors
    • - Consuming high-levels of soy
    • - Hormone therapy
    • - Cancer treatments like chemotherapy
    • - Medications
    • - Eating disorders
    • - Injury or trauma


    Polycystic ovary syndrome (PCOS) is a common hormonal imbalance in women at a reproductive age, with about 5 million Americans affected. Common signs of this disorder are infrequent or prolonged menstruation among other symptoms. There may also be high levels of androgen, the male hormone. As a result, the ovaries can develop follicles over time and are unable to produce eggs regularly.

    If you suspect PCOS or have any other symptoms, visit your doctor. He or she will have the best treatment plan for you.

    Treatment Options

    Treatment options vary depending on your condition and what hormones have been affected. It is often difficult for women to find what suits them, and it can take years to find the right solution. Upon visiting your doctor, some possible options that may be suggested include:

    • Hormone or birth control medication: Hormonal birth control can regulate your periods. This includes the pill, the patch, the birth control shot, vaginal ring, and intrauterine device (IUD). It may also help clear up acne and hair in unwanted places.

      • Hormone replacement therapy (HRT): During menopause, many women experience hot flashes and other uncomfortable symptoms. Doctors may prescribe a low dose of estrogen which replaces the diminished hormones. Be aware that this type of therapy has been linked to increased risk of stroke, breast cancer, and heart disease.

        • Anti-androgen medications: Women with high androgen hormone levels may be prescribed medications that block androgens. These medications may result in a lowered sex drive, menstrual irregularity, hot flashes, and breast tenderness among other things.

        When looking to supplement the treatment of your condition, there may be some easy, natural solutions that can help. A simple thing you can do is to monitor your environment, food, and exercise. Ensure that you are not around any plastics, pesticides, or chemicals.

        Make sure to eat a well-balanced diet to keep healthy. It has been said that a 10% reduction in body weight in some women may cause menstruation to become more regular and can even increase fertility. Another great practice is managing stress in a healthy way, such as through meditation, taking nature walks, or talking to a good friend.

        Besides getting healthy, supplementing with cannabidiol (CBD) is another hugely beneficial, and natural option. CBD is an amazing chemical compound known as a cannabinoid that is extracted from the hemp plant. It has become popularized due to its many health and wellness benefits. So what exactly can CBD do for hormonal balance?

        Disclaimer: This content is for informational purposes only. It is not provided to diagnose, treat, cure, or prevent any disease or ailment. It should not be interpreted as instruction or medical advice to displace the advice of your doctor or other medical professionals. We recommend talking to your doctor to prepare a treatment plan for any diseases or ailments.

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